A cargo ship operated by A.P. Moller-Maersk A/S lost several hundred containers in the Pacific Ocean while sailing through heavy seas from China to Los Angeles, the latest in a spate of incidents in which boxes carrying millions of dollars’ worth of goods have gone overboard. The company said the Maersk Essen, which has capacity for more than 13,000 containers, lost an estimated 750 of them on January 16 about halfway through its trans-Pacific sailing from China’s Port of Xiamen.

“All crew members are safe and a detailed cargo assessment is ongoing while the vessel continues on her journey,” Maersk said in a statement on Thursday. “The U.S. Coast Guard, flag state and relevant authorities have been notified. We view this as a very serious situation which will be investigated promptly and thoroughly.” A.P. Moller-Maersk is based in Copenhagen and the ship carries a Danish flag.