If the world doesn’t stop the region’s surging caseload, it could cost us all that we’ve done to fight the pandemic, one health official said.

 In the capital of Colombia, Bogotá, the mayor is warning residents to brace for “the worst two weeks of our lives.” Uruguay, once lauded as a model for keeping the coronavirus under control, now has one of the highest death rates in the world, while the grim daily tallies of the dead have hit records in Argentina, Brazil, Colombia and Peru in recent days.

Even Venezuela, where the authoritarian government is notorious for hiding health statistics and any suggestion of disarray, says that coronavirus deaths are up 86 percent since January. As vaccinations mount in some of the world’s wealthiest countries and people cautiously envision life after the pandemic, the crisis in Latin America — and in South America in particular — is taking an alarming turn for the worse, potentially threatening the progress made well beyond its borders.

Last week, Latin America accounted for 35 percent of all coronavirus deaths in the world, despite having just 8 percent of the global population, according to data compiled by The New York Times.

Latin America was already one of the world’s hardest hit regions in 2020, with bodies sometimes abandoned on sidewalks and new burial grounds cut into thick forest. Yet even after a year of incalculable loss, it is still one of the most troubling global hot spots, with a recent surge in many countries that is even more deadly than before.

The crisis stems in part from predictable forces — limited vaccine supplies and slow rollouts, weak health systems and fragile economies that make stay-at-home orders difficult to impose or maintain.

But the region has another thorny challenge, health officials say: living side-by-side with Brazil, a country of more than 200 million whose president has consistently dismissed the threat of the virus and denounced measures to control it, helping fuel a dangerous variant that is now stalking the continent.

Inequality, a longstanding scourge that had been easing before the pandemic, is widening once again, and millions have been tossed back into the precarious positions they thought they had escaped during a relative boom. Many are venting their anger in the streets, defying official pleas to stay home.

“They’ve taken so much from us that we’ve even lost our fear,” read a sign held by Brissa Rodríguez, 14, at a protest with thousands of others in Bogotá on Wednesday.