The Biden administration will finalize its first new climate rule Thursday, slashing the use of greenhouse gases warming the planet at a rate hundreds to thousands of times higher than carbon dioxide.

The Environmental Protection Agency regulation, which establishes a program to cut the use and production of chemicals known as hydrofluorocarbons in the United States by 85 percent over the next 15 years, implements a law passed by Congress last year. There is broad bipartisan support for curbing these super-pollutants, which are short-lived and often used in refrigeration and air conditioning.White House officials said the new rule tackles global warming while supporting jobs to manufacture new alternatives.

“It’s a win on climate and a win on jobs, and American competitiveness,” Gina McCarthy, the White House national climate coordinator, told reporters in an online briefing Wednesday evening. “It’s really — frankly, folks — a very big deal.”

But the measure comes at a fraught moment for President Biden, who is struggling to shepherd the rest of his climate agenda through Congress. Democrats are trying pass a pair of bills aimed at expanding the adoption of solar panels, wind turbines and electric vehicles, but divisions between the party’s moderate and liberal wings have complicated their passage.

Thursday’s announcement, by contrast, shows how much easier it is for federal agencies to tackle greenhouse gas emissions when empowered by legislation.

The EPA is putting a cap on hydrofluorocarbons through 2023, allocating allowances for companies to make or import them over the next two years. The agency will scale back their use further through 2036 with additional regulation.

Avipsa Mahapatra, climate campaign leader at the Environmental Investigation Agency (EIA), a nongovernmental advocacy group, praised regulators for tackling what she called “the most potent super-pollutants known to mankind at the moment.”

“This is a landmark EPA rulemaking,” she said.

HFCs were once an environmental solution — not a problem. They replaced other chemicals that, when released into the atmosphere, eroded the Earth’s protective ozone layer. But their heat-trapping properties still exacerbated global warming. Five years ago, world leaders signed the Kigali Amendment, an update to the 1987 Montreal Protocol, to rein in these super-pollutants.

But President Donald Trump never submitted the treaty for Senate ratification, and his administration rolled backed Obama-era policies aimed at meeting the nation’s commitments under Kigali.

Biden promised to send the treaty to Capitol Hill just after taking office but has yet to do so. “We know he’s committed to taking that action,” McCarthy said, “but I don’t have a time window to discuss with you.”